© 2023 Connecticut Public

FCC Public Inspection Files:
WEDH · WEDN · WEDW · WEDY · WNPR
WPKT · WRLI-FM · WEDW-FM · Public Files Contact
Play Live Radio
Next Up:
0:00
0:00
Available On Air Stations

The FDA has authorized Merck's COVID pill for home use — the 2nd in 2 days

A photo provided by Merck of its new pill, molnupiravir, to treat COVID-19. Copyright © 2009-2021 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, N.J., U.S.A. All rights reserved.
Merck & Co., Inc.
A photo provided by Merck of its new pill, molnupiravir, to treat COVID-19. Copyright © 2009-2021 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, N.J., U.S.A. All rights reserved.

The U.S. Food and Drug Administration has authorized the second antiviral pill to treat COVID-19 at home.

The medicine, called molnupiravir and made by Merck and Ridgeback Biotherapeutics, is taken twice a day for five days. Merck says it will have 10 million packs available by the end of the month.

These new antiviral pills could totally change how people treat COVID-19 infections at home, since the only FDA-authorized treatment for nonhospitalized COVID-19 patients is monoclonal antibodies, which typically require an intravenous infusion.

The agency authorized Pfizer's Paxlovid treatment for COVID-19 on Wednesday.

"Today's authorization provides an additional treatment option against the COVID-19 virus in the form of a pill that can be taken orally," Dr. Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research, said Thursday.

"Molnupiravir is limited to situations where other FDA-authorized treatments for COVID-19 are inaccessible or are not clinically appropriate and will be a useful treatment option for some patients with COVID-19 at high risk of hospitalization or death," she added.

The drug works by introducing mutations into the SARS-CoV-2 virus's genetic code to prevent it from replicating.

FDA didn't authorize molnupiravir for use in patients younger than 18 because the drug may interfere with bone and cartilage growth.

The agency also said the medicine is not recommended for use during pregnancy because animal studies suggested it could harm the fetus. The FDA warned people who may become pregnant to use a reliable method of birth control while taking molnupiravir until four days after the final dose. Men who are sexually active with women who may become pregnant are advised to use birth control while taking molnupiravir and for at least three months after the final dose.

The pill is available by prescription only, and treatment should begin as soon as possible after a COVID-19 diagnosis and within five days of the onset of symptoms in order to treat mild-to-moderate disease, the FDA said.


A version of this story originally appeared in the Morning Edition live blog.

Copyright 2021 NPR. To see more, visit https://www.npr.org.

Scott Hensley edits stories about health, biomedical research and pharmaceuticals for NPR's Science desk. During the COVID-19 pandemic, he has led the desk's reporting on the development of vaccines against the coronavirus.
Joe Hernandez

Stand up for civility

This news story is funded in large part by Connecticut Public’s Members — listeners, viewers, and readers like you who value fact-based journalism and trustworthy information.

We hope their support inspires you to donate so that we can continue telling stories that inform, educate, and inspire you and your neighbors. As a community-supported public media service, Connecticut Public has relied on donor support for more than 50 years.

Your donation today will allow us to continue this work on your behalf. Give today at any amount and join the 50,000 members who are building a better—and more civil—Connecticut to live, work, and play.

Related Content